Photo Gallery | Massive storm through the Mid-South spawns tornadoes, heavy rains in MS
The storm started on the Mississippi coast in Stone County where officials said at least two trailer homes were damaged.
At least two people were killed and there are reports of widespread power outages.
First responders are assessing the damages.
In Pearl located in Central Mississippi, heavy rains forced residents out of their homes.
Rainfall dumped enough water to submerge streets all the way up to people's driveways.
There were similar scenes in several parts around Jackson, Mississippi.